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U.S. manufacturing kept up its momentum in November 2025, with major announcements spanning pharmaceuticals, electronics, renewable energy, transportation and industrial equipment. Biopharma firms invested billions to boost domestic supply chains and advanced treatments; energy equipment manufacturers and semiconductor companies unveiled new U.S. plants to onshore production; and automotive and aerospace companies expanded to meet demand for hybrid vehicles and commercial aircraft. Collectively, the month’s announcements involve tens of billions in capital spending and thousands of new jobs across the country.
British pharmaceutical giant AstraZeneca will invest $2 billion to build a new manufacturing campus in Maryland, including a 60 acre site in Frederick and an expansion of its Gaithersburg biologics facility. The multi facility project is expected to create 2,600 jobs and strengthen the company’s U.S. supply chain.
CEO Pascal Soriot said the investment marks “a landmark moment for Maryland and American patients,” adding that AstraZeneca is deepening its commitment to the state and the country: “Today marks a landmark moment for Maryland and American patients…we are deepening our long standing commitment to Maryland, supporting 2,600 jobs-- catalysing economic growth and bringing our extensive rare disease portfolio onshore” The new facilities will support production of medicines for rare diseases and biologics.
Novartis announced plans to establish an end to end manufacturing hub in the Research Triangle region of North Carolina. The expansion includes 700,000 square feet of new and upgraded facilities in Durham and Morrisville and will create 700 jobs.
CEO Vas Narasimhan described the investment as a commitment to U.S. innovation: “This announcement is a commitment to American innovation and to the patients we serve. By building a full, end to end manufacturing presence in North Carolina for our broader portfolio, we are expanding our capacity to deliver medical breakthroughs, securing a more resilient US supply chain” The hub will increase Novartis’ capacity for gene therapy manufacturing and support its commercial gene therapy pipeline.
Portuguese pharmaceutical company Hovione completed a $100 million expansion of its East Windsor, New Jersey campus, adding 200,000 square feet and two large spray dryers to double its U.S. spray drying capacity.
CEO Jean Luc Herbeaux said the investment strengthens Hovione’s leadership in spray drying and supports customers developing complex medicines: “This investment reinforces Hovione’s leadership in spray drying – a core technology platform where we have built extensive know-how and capabilities. By continuing to advance our platforms and expand capacity in the U.S., we are strengthening the foundation that enables our partners to bring complex medicines to patients more efficiently.”
Poultry processor Pilgrim’s (part of JBS Foods) broke ground on a prepared foods plant in Walker County, Georgia. The $400 million facility will produce just bare® and Pilgrim’s® brand products and create more than 630 jobs.
“Expanding the Pilgrim’s footprint in Georgia highlights our ongoing commitment to the region and our company’s long-term growth strategy,” said Fabio Sandri, Pilgrim’s CEO. The company also pledged $1 million to local charities.
First Solar inaugurated a 2.4 million square foot manufacturing facility in New Iberia Parish, Louisiana. The $1.1 billion plant, equipped with artificial intelligence driven production systems, will produce Series 7 photovoltaic modules and is expected to create more than 800 jobs. CEO Mark Widmar called the project a commitment to U.S. energy leadership: ““This is more than just a manufacturing facility. It’s a commitment to American energy dominance, affordable electricity, growth and prosperity.”
Rockwell Automation will build a new manufacturing site exceeding 1 million square feet in southeastern Wisconsin, part of a $2 billion capital program across its U.S. facilities. CEO Blake Moret said designing a new facility allows Rockwell to reimagine industrial operations: “Designing a new facility presents the opportunity to create the future of industrial operations, with highly orchestrated production.”
Toyota announced a $912 million investment to boost hybrid vehicle production across its U.S. plants in West Virginia, Kentucky, Mississippi, Tennessee and Missouri, adding 252 jobs. Senior vice president Kevin Voelkel explained that the expansion aligns with Toyota’s philosophy of building where it sells: “Toyota’s philosophy is to build where we sell, and by adding more American jobs and investing across our U.S. footprint, we continue to stay true to that philosophy.”
Materials science company Entegris celebrated the grand opening of its 135,000 square foot Manufacturing Center of Excellence in Colorado Springs, Colorado. The facility expands production of filtration and purification products and semiconductor wafer carriers and is supported by up to $100 million in government incentives.
“The U.S. semiconductor industry's strength hinges on a reliable and advanced domestic supply chain of critical process chemistries and solutions,” said Entegris president and CEO Dave Reeder. “We are very proud that this state-of-the-art facility will be instrumental in realizing that vision for our customers, and building a more resilient semiconductor manufacturing ecosystem here in the U.S.”
Power management company Eaton is investing $6.8 million to expand its Middlesex, North Carolina facility by 40,000 square feet, adding 30 jobs. Traci Melville, president of Eaton’s Fluid and Electrical Distribution Division, noted “This expansion underscores our ongoing commitment to investing in the Middlesex facility and enhancing our ability to serve customers with greater efficiency and responsiveness.”
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South Korean transformer manufacturer Hyosung HICO will invest $157 million to expand its U.S. manufacturing headquarters in Memphis, Tennessee, increasing capacity by 50 percent and creating 240 new jobs. President Jason E. Neal described the expansion as a shared achievement: ““This additional expansion reflects our shared success with the State of Tennessee and the partnership between our U.S. operations and our headquarters in South Korea.”
Canadian owned Cancoil USA will construct a new manufacturing operations center in Jacksonville, Texas, investing more than $28 million and creating 120 jobs. Spokeswoman Monika Datta said the facility will anchor U.S. operations and reflects confidence in the region’s workforce: “Our decision to invest in Jacksonville reflects our confidence in the region’s skilled workforce and its strong business climate. We look forward to building lasting relationships with the community and contributing to its economic vitality.
FormFactor, a leading supplier of semiconductor test equipment, will invest over $140 million to build an advanced manufacturing facility in Farmers Branch, Texas. Said CEO Mike Slessor “As the world’s leading supplier of advanced probe cards, which are used by global manufacturers of the logic and memory chips at the heart of AI revolution and data centers, we play a critical role in the global semiconductor industry.
Defense contractor Kratos Defense & Security Solutions opened a 22,500 square foot propulsion manufacturing facility in Auburn Hills, Michigan designed for concurrent production of up to 50,000 Spartan turbojet engines per year. Steve Fendley, president of Kratos’ Unmanned Systems Division, emphasized the importance of a production first mindset: “Our production-first mindset has been key to our success in realizing high-reliability, military-grade engines with key operational features that can be produced affordably and delivered at high rates. This is a result of our focus on producibility and cost right from the start, rather than the traditional performance first, manufacturability and cost second approach.”
Aerospace manufacturer Boeing is investing more than $1 billion to expand its 787 production site in North Charleston, South Carolina, adding 1,000 new jobs and building new final assembly lines. Boeing Commercial Airplanes president and CEO Stephanie Pope said the project responds to strong demand for the 787: “"We continue to see strong demand for the 787 Dreamliner family and its market-leading efficiency and versatility. We are making this significant investment today to ensure Boeing is ready to meet our customer's needs in the years and decades ahead.”
German automotive supplier MAHLE will invest $6.8 million to expand its Lockport, New York facility, relocating a research and testing center from Michigan. The project will add 11 jobs and retain 226. Vice president Stefan Land thanked officials for enabling growth: “We sincerely appreciate the strong support from state and local officials. Their partnership plays a vital role in enabling our growth and strengthening our long term commitment to the region”
The expansion will enhance thermal management R&D capabilities.
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Polyzent Trading LLC plans to invest $1.1 million to establish its first U.S. manufacturing facility in Lynchburg, Virginia, producing polyethylene stretch film. Founder Dhaivat Patel said local production will shorten lead times and improve quality: “Local extrusion means shorter lead times, consistent quality, and reduced dependence on foreign stretch-film imports. As we expand our capabilities into specialty films and sustainable packaging solutions, we invite Virginia manufacturers and national supply-chain partners to support American-made film and help build a stronger industrial future.” The 20 job facility will enable Polyzent to serve East Coast customers.
Irish generator manufacturer CEL Critical Power established its first U.S. manufacturing facility in James City County, Virginia, investing $5.225 million. The plant will build generator enclosures and is expected to hire 250 people initially, rising to 500 by 2030. Group managing director Niall McFadden thanked state and local partners: “It is no surprise that Virginia consistently ranks among the top locations for business in the United States, offering a great supply chain ecosystem, excellent infrastructure and a large pool of technical talent.”
Australian technical textiles company VectorTex will invest more than $6 million to build its first U.S. production and innovation hub in Elizabethtown, North Carolina. The 25,000 square foot facility will create 44 jobs. Technical Business Development Manager Callum de Vries said the investment strengthens service to U.S. customers: “This investment strengthens our ability to serve customers across the United States, shortening supply chains and strengthening our global engineering, quality and production capability.
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