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The pharmaceutical manufacturing industry in the United States is a vital component of the nation's healthcare system and economy. This sector plays a crucial role in developing, producing, and distributing medications that improve and save lives. With a strong emphasis on innovation and quality, U.S. pharmaceutical manufacturers are at the forefront of medical advancements, ensuring that patients have access to cutting-edge treatments.
In this article, we will explore some of the leading pharmaceutical manufacturers in the United States, explore some of the latest trends and statistics on this powerful industry, based on data collected by MNI.
MNI, compiler and publisher of industrial business profiles for the U.S. industrial sector and informational engine behind IndustrySelect, surveyed the nation’s more than 1,200 U.S. pharmaceutical manufacturers, collecting key data points on this essential industry.
• There are currently 1,296 pharmaceutical manufacturers in the U.S.
• 220,769 workers are employed in this essential industry (2025 data), with the industry accounting for nearly a quarter of all chemical industry employment
• Employment among pharmaceutical companies has increased 3.22% in 2024.
• Average reported sales for U.S. pharmaceutical manufacturers ran $404 billion in 2024.
• 320 or 25% of pharmaceutical companies in the United States import raw materials.
• 585 or 45% distribute internationally, running past the national average among all manufacturers of 29%
• 1% are woman-owned
• The Eastern region of the U.S. accounts for the most pharmaceutical manufacturers, encompassing 31%, followed by the U.S. South with 28%.
Related: Key Facts & Trends in the U.S. Chemical Industry
| Top Companies | City | State | Number of Employees |
|---|---|---|---|
| Eli Lilly & Co. | Indianapolis | IN | 10,157 |
| Merck & Co., Inc. | West Point | PA | 9,500 |
| Merck & Co., Inc. | Rahway | NJ | 6,000 |
| Amgen, Inc. | Thousand Oaks | CA | 5,500 |
| Novartis Pharmaceuticals Corp. | East Hanover | NJ | 4,779 |
| Pfizer, Inc. | New York | NY | 4,500 |
| AstraZeneca Pharmaceuticals LP | Gaithersburg | MD | 3,500 |
| Endo Pharmaceuticals, Inc. | Malvern | PA | 3,500 |
| Perrigo Co. | Allegan | MI | 3,500 |
| AbbVie, Inc. | North Chicago | IL | 3,400 |
Tap into a booming market! Reach 6,400+ medical, biotech, & pharmaceutical companies and their 16,700+ decision-makers with the Medical, Biotech, & Pharmaceutical Company Database, only from MNI.
Eli Lilly & Co. (Indianapolis, IN)
Eli Lilly & Co., headquartered in Indianapolis, Indiana, is a global leader in pharmaceutical innovation. Known for its pioneering work in biotechnology, chemistry, and genetic medicine, Lilly focuses on addressing some of the world's most significant health challenges. The company has a rich history of developing groundbreaking treatments for conditions such as diabetes, cancer, and mental health disorders.
Merck & Co., Inc. (West Point, PA)
Merck & Co., Inc., with a major facility in West Point, Pennsylvania, is renowned for its contributions to vaccine development and pharmaceutical research. The West Point campus is a hub for Merck's manufacturing and supply operations, playing a crucial role in the production of vaccines and other essential medicines.
Merck & Co., Inc. (Rahway, NJ)
Merck's Rahway, New Jersey site serves as the company's global headquarters and a center for research and development. This location is integral to Merck's mission of advancing health solutions through innovative science and technology. The Rahway facility supports a wide range of activities, from drug discovery to regulatory affairs.
Amgen, Inc. (Thousand Oaks, CA)
Amgen, Inc., based in Thousand Oaks, California, is one of the world's leading biotechnology companies. Amgen is dedicated to discovering, developing, and delivering innovative human therapeutics. The company's focus areas include oncology, cardiovascular disease, and inflammation, with a strong emphasis on biologics.
Novartis Pharmaceuticals Corp. (East Hanover, NJ)
Novartis Pharmaceuticals Corp., located in East Hanover, New Jersey, is a key player in the global pharmaceutical industry. Novartis is committed to improving and extending people's lives through innovative medicines. The East Hanover site is a major center for the company's operations in the United States.
Pfizer, Inc. (New York, NY)
Pfizer, Inc., headquartered in New York City, is a global biopharmaceutical company known for its extensive portfolio of medicines and vaccines. Pfizer's new headquarters at Hudson Yards reflects its commitment to innovation and its role in addressing some of the most pressing health challenges worldwide.
AstraZeneca Pharmaceuticals LP (Gaithersburg, MD)
AstraZeneca Pharmaceuticals LP, based in Gaithersburg, Maryland, is a global, science-led biopharmaceutical company. The Gaithersburg campus is one of AstraZeneca's three global research and development centers, focusing on innovative treatments for diseases such as cancer and respiratory conditions.
Endo Pharmaceuticals, Inc. (Malvern, PA)
Endo Pharmaceuticals, Inc., headquartered in Malvern, Pennsylvania, specializes in developing and delivering life-enhancing therapies. Endo's focus areas include specialty medicines, sterile injectables, and high-value generic products. The company is dedicated to addressing unmet patient needs through innovative solutions.
Perrigo Co. (Allegan, MI)
Perrigo Co., located in Allegan, Michigan, is a leading global provider of over-the-counter health and wellness solutions. With a history dating back to 1887, Perrigo is committed to delivering high-quality, affordable healthcare products that improve the lives of consumers around the world.
AbbVie, Inc. (North Chicago, IL)
AbbVie, Inc., based in North Chicago, Illinois, is a global biopharmaceutical company focused on discovering and delivering innovative medicines. AbbVie's research and development efforts are aimed at addressing some of the world's most complex and serious diseases, including cancer, immunology, and neuroscience.
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Article Sources:
Senior Scientist - Vaccines and Advanced Biotechnologies Process R&D
Demolition is on hold at Novartis HQ in East Hanover - Daily Record
Mayor Adams Joins Pfizer CEO for Grand Opening of New NYC Headquarters
Gensler reveals rendering of Pfizer HQ conversion in New York - Dezeen
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